Home Categories Pharmaceutical intermediates 4-Hydroxy-1-methyl-2(1H)-quinolone
BD9980155

4-Hydroxy-1-methyl-2(1H)-quinolone , 98% , 1677-46-9

CAS NO.:1677-46-9

Empirical Formula: C10H9NO2

Molecular Weight: 175.18

MDL number: MFCD00024052

EINECS: 216-830-3

Pack Size Price Stock Quantity
1g RMB62.40 In Stock
5g RMB211.20 In Stock
25g RMB803.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 269-271 °C (lit.)
Boiling point: 306.47°C (rough estimate)
Density  1.326
refractive index  1.5060 (estimate)
pka 4.50±1.00(Predicted)
form  powder to crystal
color  Light yellow to Brown to Dark green
CAS DataBase Reference 1677-46-9(CAS DataBase Reference)
EPA Substance Registry System 2(1H)-Quinolinone, 4-hydroxy-1-methyl- (1677-46-9)

Description and Uses

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :

  • 3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone
  • 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one
  • 3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one
  • 3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  FG7350000
Hazard Note  Irritant
HS Code  2933499090
Toxicity mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01354,

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