3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one , 95% , 503615-03-0

CAS NO.：503615-03-0

Empirical Formula: C15H17N3O4

Molecular Weight: 303.31

MDL number: MFCD19440872

PRODUCT Properties

• Boiling point: 506.5±50.0 °C(Predicted)
• Density: 1.356
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
• form: Solid
• pka: 3.11±0.20(Predicted)
• color: Light Yellow
• InChI: InChI=1S/C15H17N3O4/c19-15-14(16-8-10-22-11-9-16)2-1-7-17(15)12-3-5-13(6-4-12)18(20)21/h2-6H,1,7-11H2
• InChIKey: LBFAEOWNWSDWRZ-UHFFFAOYSA-N
• SMILES: C1(=O)N(C2=CC=C([N+]([O-])=O)C=C2)CCC=C1N1CCOCC1

Description and Uses

3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one is a reagent in the synthesis of 4,5-dehydro Apixaban (D229385) an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation