Home Categories Organic Chemistry 3,3-Difluoropyrrolidine hydrochloride
BD9487131

3,3-Difluoropyrrolidine hydrochloride , 97% , 163457-23-6

CAS NO.:163457-23-6

Empirical Formula: C4H8ClF2N

Molecular Weight: 143.56

MDL number: MFCD03788948

EINECS: 626-850-8

Pack Size Price Stock Quantity
250mg RMB25.60 In Stock
1g RMB58.40 In Stock
5g RMB180.00 In Stock
10g RMB321.60 In Stock
25g RMB753.60 In Stock
100g RMB2371.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 128-130°C
storage temp.  Inert atmosphere,Room Temperature
form  solid
color  White to off white
Sensitive  Hygroscopic
InChIKey YYVPZQADFREIFR-UHFFFAOYSA-N
CAS DataBase Reference 163457-23-6(CAS DataBase Reference)

Description and Uses

3,3-Difluoropyrrolidine hydrochloride can be used as a building block in the synthesis of:

  • Triazole substituted prolyl difluoropyrrolidines as potential inhibitors of dipeptidyl peptidase-4.
  • Dual leucine zipper kinase (DLK) inhibitors.

It can be also used as a reactant in the preparation of cyclic and acyclic β-aminofluoroalkenes via allylic amination using the Pd catalyst.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT, HYGROSCOPIC
HS Code  29339900

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