2-(4-Methoxybenzyl)isothiazolidine 1,1-dioxide , 95% , 158089-76-0
| Pack Size | Price | Stock | Quantity |
| 5g | RMB1412.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >47°C (dec.) |
| Boiling point: | 397.0±44.0 °C(Predicted) |
| Density | 1.279±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly) |
| form | Solid |
| pka | -4.81±0.20(Predicted) |
| color | Light Orange to Orange |
| CAS DataBase Reference | 158089-76-0 |
Description and Uses
The antibacterial properties of the sulfonamides were discovered in the mid-1930s following an incorrect hypothesis but after observing the results carefully and drawing correct conclusions. Prontosil rubrum, a red dye, was one of a series of dyes examined by Gerhard Domagk of Bayer of Germany in the belief that it might be taken up selectively by certain pathogenic bacteria and not by human cells, in a manner analogous to the way in which the Gram stain works, and, therefore, serve as a selective poison to kill these cells. The dye, indeed, proved to be active in vivo against streptococcal infections in mice. Curiously, it was not active in vitro.
2-(4-Methoxybenzyl)isothiazolidine 1,1-Dioxide (cas# 158089-76-0) is a useful a reagent in palladium-catalyzed α-arylation of sultams with aryl and heteroaryl iodides.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
