5,7-Dihydroxychromone , 98+% , 31721-94-5
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB4277.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 232-273℃ |
| Boiling point: | 399℃ |
| Density | 1.563 |
| Flash point: | 171℃ |
| storage temp. | 2-8°C |
| solubility | insoluble in H2O; ≥5.41 mg/mL in EtOH with gentle warming; ≥7.05 mg/mL in DMSO |
| form | solid |
| pka | 6.57±0.20(Predicted) |
| color | White to light yellow |
Description and Uses
5,7-Dihydroxychromone is a flavone decomposition product that has been found in A. hypogaea and has diverse biological activities, including antimicrobial, antioxidant, and neuroprotective properties. It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC50s = 18 and 26 μM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium. 5,7-Dihydroxychromone (0.4, 2, and 10 μM) reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells when used at concentrations ranging from 0.08 to 10 μM.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
