1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate , 98% , 136705-77-6

Synonym(s):
(R,R)-Et-DUPHOS-Rh

CAS NO.：136705-77-6

Empirical Formula: C31H48F3O3P2RhS

Molecular Weight: 722.62

MDL number: MFCD00269860

PRODUCT Properties

• storage temp.: Refrigerator (+4°C)
• form: crystal
• color: orange
• Sensitive: Air Sensitive
• Exposure limits: ACGIH: TWA 1 mg/m3; NIOSH: IDLH 100 mg/m3; TWA 0.1 mg/m3

Description and Uses

DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

Catalyst for:

• Stereoselective synthesis of δ-amino acid derivatives via asymmetric hydrogenation of acetylaminopentenoic acid derivatives
• Stereoselective synthesis of manzacidins A and C via stereoselective hydrogenation
• Stereoselective synthesis of tetracyclic core of manzamine A via Rh-catalyzed asymmetric hydrogenation, diastereoselective Diels-Alder reaction, Eschenmoser-Tanabe fragmentation, Chang′s amide formation, and Hofmann rearrangement
• Asymmetric preparation of chiral Cbz-aminodifluorobutyric acid Me ester and its analogs
• Biphasic catalytic hydrogenations in ionic liquids with addition of water as a second solvent
• Preparation of cyclobutane-containing amino acids via asymmetric hydrogenations of cyclobutyl enamides
• Asymmetric preparation of both enantiomers of (dimethoxycoumaryl)alanine as suitable fluorescent peptide labels

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 24/25-36/37-26
• WGK Germany: 3
• HS Code: 29310099