tert-Butyl(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate , 95% , 869310-84-9
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB104.80 | In Stock |
|
| 250mg | RMB159.20 | In Stock |
|
| 1g | RMB515.20 | In Stock |
|
| 5g | RMB2004.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 344.2±27.0 °C(Predicted) |
| Density | 1.033±0.06 g/cm3(Predicted) |
| form | Liquid |
| pka | 12.22±0.46(Predicted) |
| color | Colorless to light yellow |
Description and Uses
t-Boc-N-Amido-PEG2-propargyl is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
