Home Categories tert-Butyl(2-(2-bromoethoxy)ethyl)carbamate
BD0460245

tert-Butyl(2-(2-bromoethoxy)ethyl)carbamate , 95% , 164332-88-1

CAS NO.:164332-88-1

Empirical Formula: C9H18BrNO3

Molecular Weight: 268.15

MDL number: MFCD24167474

Pack Size Price Stock Quantity
100mg RMB79.20 In Stock
250mg RMB132.00 In Stock
1g RMB353.60 In Stock
5g RMB1257.60 In Stock
25g RMB4625.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 336.6±22.0 °C(Predicted)
Density  1.283±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  Soluble in Water, DMSO, DCM, DMF
pka 12.19±0.46(Predicted)
form  Liquid
color  Colorless to light yellow

Description and Uses

Tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate (t-boc-N-amido-PEG2-bromide) is a PEG derivative containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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