Rabeprazole , 98% , 117976-89-3

CAS NO.：117976-89-3

Empirical Formula: C18H21N3O3S

Molecular Weight: 359.44

MDL number: MFCD00868879

EINECS: 601-501-2

PRODUCT Properties

• Melting point: 99-100° (dec)
• Boiling point: 603.9±65.0 °C(Predicted)
• Density: 1.33±0.1 g/cm3(Predicted)
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Solid
• pka: 9.57±0.10(Predicted)
• color: Light Brown to Very Dark Brown
• BCS Class: 1,3
• Stability: Hygroscopic

Description and Uses

Rabeprazole, a proton pump inhibitor (PPI), effectively lowers stomach acid production to alleviate conditions such as gastroesophageal reflux disease (GERD), ulcers, and other issues caused by excessive acid production. It belongs to the benzimidazole derivative family, sharing a structural similarity with omeprazole, another PPI. Rabeprazole hampers the activity of the gastric proton pump responsible for acid production. By binding to the pump, it obstructs the release of hydrogen ions into the stomach, ultimately reducing acid production. Furthermore, rabeprazole exhibits various biochemical and physiological effects. A study conducted on rats revealed that rabeprazole effectively decreases the gastric proton pump′s activity, leading to a decrease in gastric acid secretion.

Rabeprazole is used to treat hyperacidity. It is a proton pump inhibitor that helps heal gastrointestinal ulcers, treats gastroesophageal reflux disease, and also treats hypersecretory disorders.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H413
• Precautionary statements: P264-P270-P301+P312-P330-P501
• Hazard Codes: Xi
• Risk Statements: 36/38
• Safety Statements: 26-37/39