Ethyl 2-(dimethoxyphosphoryl)acetate , 97% , 311-46-6

Synonym(s):
Ethoxycarbonylmethylphosphonic acid dimethylester;Phosphonoacetic acid P,P-dimethyl ethylester

CAS NO.：311-46-6

Empirical Formula: C6H13O5P

Molecular Weight: 196.14

MDL number: MFCD00015677

EINECS: 206-222-6

PRODUCT Properties

• Boiling point: 134 °C10 mm Hg(lit.)
• Density: 1.188 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.435(lit.)
• Flash point: 99 °C
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: clear liquid
• color: Colorless to Almost colorless
• BRN: 1777603
• InChI: InChI=1S/C6H13O5P/c1-4-11-6(7)5-12(8,9-2)10-3/h4-5H2,1-3H3
• InChIKey: HUNISAHOCCASGM-UHFFFAOYSA-N
• SMILES: C(OCC)(=O)CP(OC)(OC)=O

Description and Uses

Reactant for synthesis of:

• Non-nucleoside inhibitors of HCV polymerase NS5B
• Neuropeptide Y1 receptor antagonists
• Alkenylcarboxylates from Horner-Wadsworth-Emmons reactions

Reactant for:

• Enantioselective transfer hydrogenation for preparation of the C7-C14 fragment of ulapualide A
• Intramolecular Michael reactions
• Olefination of peptidyl aldehydes with stabilized ylides

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
• Hazard Codes: Xi
• Safety Statements: 23-24/25
• WGK Germany: 3
• HS Code: 2920907090