Home Categories Organic Chemistry Trimethyl phosphonoacetate
A7726212

Trimethyl phosphonoacetate , 95% , 5927-18-4

Synonym(s):
(Carboxymethyl)phosphonic acid trimethyl ester;NSC 84262

CAS NO.:5927-18-4

Empirical Formula: C5H11O5P

Molecular Weight: 182.11

MDL number: MFCD00008452

EINECS: 227-663-0

Pack Size Price Stock Quantity
5g RMB23.20 In Stock
25G RMB24.00 In Stock
100G RMB55.20 In Stock
250g RMB95.20 In Stock
500G RMB167.20 In Stock
2.5kg RMB719.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 242 °C
Boiling point: 118 °C0.85 mm Hg(lit.)
Density  1.125 g/mL at 25 °C(lit.)
refractive index  n20/D 1.437(lit.)
Flash point: >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Liquid
Specific Gravity approximate 1.265g/ml (20℃)
color  Clear colorless to light yellow
Water Solubility  Slightly miscible with water.
BRN  1865177
LogP -0.680 (est)
CAS DataBase Reference 5927-18-4(CAS DataBase Reference)
NIST Chemistry Reference Trimethyl phosphonoacetate(5927-18-4)
EPA Substance Registry System Acetic acid, (dimethoxyphosphinyl)-, methyl ester (5927-18-4)

Description and Uses

Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
Safety Statements  23-24/25
WGK Germany  3
9
TSCA  Yes
HS Code  29310095

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