Home Categories Chemical Reagents 2-(Benzyloxy)acetyl chloride
BD7817631

2-(Benzyloxy)acetyl chloride , 95%GC , 19810-31-2

CAS NO.:19810-31-2

Empirical Formula: C9H9ClO2

Molecular Weight: 184.62

MDL number: MFCD00010768

EINECS: 629-534-8

Pack Size Price Stock Quantity
1g RMB24.00 In Stock
5g RMB77.60 In Stock
10g RMB150.40 In Stock
25g RMB354.40 In Stock
100g RMB1392.80 In Stock
500g RMB5217.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 120 °C (decomp)
Boiling point: 84-87 °C/0.4 mmHg (lit.)
Density  1.17 g/mL at 25 °C (lit.)
refractive index  n20/D 1.523(lit.)
Flash point: >230 °F
storage temp.  2-8°C
form  Powder or Cyrstals
color  White
Water Solubility  Reacts with water.
Sensitive  Moisture Sensitive
BRN  1947363
InChI InChI=1S/C9H9ClO2/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2
InChIKey QISAUDWTBBNJIR-UHFFFAOYSA-N
SMILES C(Cl)(COCC1=CC=CC=C1)=O

Description and Uses

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  14-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
10-19
HazardClass  8
PackingGroup  III
HS Code  29189900

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