BD5139641
12-((tert-Butoxycarbonyl)amino)dodecanoicacid , 98% , 18934-81-1
Synonym(s):
12-(Boc-amino)dodecanoic acid
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB65.60 | In Stock |
|
| 1g | RMB167.20 | In Stock |
|
| 5g | RMB600.80 | In Stock |
|
| 25g | RMB2606.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 83.5-84.5 °C |
| Boiling point: | 454.5±18.0 °C(Predicted) |
| Density | 0.997±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| pka | 4.78±0.10(Predicted) |
| BRN | 1980302 |
Description and Uses
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501 |
| WGK Germany | 3 |
