PRODUCT Properties
| Melting point: | 280-280.5 °C (decomp) |
| Boiling point: | 547.1±50.0 °C(Predicted) |
| Density | 2.5688 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | It is soluble in alcohol, slightly soluble in ether and water, very slightly soluble in chloroform and practically insoluble in benzene. |
| form | powder to crystal |
| pka | 1.13±0.10(Predicted) |
| color | White power |
| Water Solubility | 1.28g/L(25 ºC) |
Description and Uses
Radiopaque agent: Acetrizoic acid (trade names Gastrografina, Urografina in Portugal) is a palatable lemon-flavored water-soluble iodinated radiopaque X-ray contrast medium for oral or rectal administration only. Acetrizoic acid is indicated for radiographic examination of segments of the gastrointestinal tract (esophagus, stomach, proximal small intestine, and colon). The preparation is particularly indicated when a more viscous agent such as barium sulfate, which is not water-soluble, is not feasible or is potentially dangerous. Administration of hypertonic Gastrografin solutions may lead to hypovolemia and hypotension due to fluid loss from the intestine.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| RTECS | DG0887000 |
| HS Code | 2924.29.7790 |
| Toxicity | LD50 orl-mus: 20 g/kg FRPSAX 18,33,63 |
