Home Categories N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide
BD4818341

N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide , 98% , 432531-71-0

Synonym(s):
MLKL Inhibitor, Necrosulfonamide - CAS 432531-71-0 - Calbiochem

CAS NO.:432531-71-0

Empirical Formula: C18H15N5O6S2

Molecular Weight: 461.47

MDL number:

Pack Size Price Stock Quantity
5mg RMB328.00 In Stock
10mg RMB556.00 In Stock
25mg RMB944.00 In Stock
50mg RMB1600.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  +2C to +8C
solubility  DMSO:100.0(Max Conc. mg/mL);216.7(Max Conc. mM)
form  Dark yellow solid
color  Light yellow to yellow

Description and Uses

Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

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