Methyl1-methylpiperidine-3-carboxylate , 97% , 1690-72-8

CAS NO.：1690-72-8

Empirical Formula: C8H15NO2

Molecular Weight: 157.21

MDL number: MFCD00128793

EINECS: 210-314-1

PRODUCT Properties

• Boiling point: bp12 83-84°
• Density: 1.013±0.06 g/cm3(Predicted)
• refractive index: nD25 1.4520
• storage temp.: 2-8°C
• pka: pKa (20°): 8.66
• CAS DataBase Reference: 1690-72-8(CAS DataBase Reference)

Description and Uses

Methyl 1-methylpiperidine-3-carboxylate belongs to the class of organic compounds known as piperidinecarboxylic acids. Piperidinecarboxylic acids are compounds containing a piperidine ring with a carboxylic acid group. Methyl 1-methylpiperidine-3-carboxylate is a strong basic compound (based on its pKa). It could be used to synthesize (1-methylpiperidin-3-yl)methanol. The specific steps are shown as follows: into a 500 mL round bottom flask containing a solution of methyl 1-methylpiperidine-3- carboxylate (12.0 g, 76 mmol) in tetrahydrofuran (500 mL) was added lithium aluminumhydride (4.3 g, 114 mmol) in portions at 0 °C. The reaction mixture was stirred at room temperature for 1 h. The reaction was quenched with methanol at 0 °C, and the precipitated solid was filtered through celite. The filtrate was concentrated and the crude was purified by flash chromatography eluting with methanol in dichloromethane (5-10percent) to afford (1-methylpiperidin-3-yl)methanol as a solid.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2933399990