2-(Prop-2-yn-1-yl)octanoicacid , 95% , 96017-59-3

CAS NO.：96017-59-3

Empirical Formula: C11H18O2

Molecular Weight: 182.26

MDL number: MFCD00946863

PRODUCT Properties

• Boiling point: 287.1±23.0 °C(Predicted)
• Density: 0.94
• refractive index: 1.4450-1.4510
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
• form: oil
• pka: 4.24±0.21(Predicted)
• color: Colorless
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months

Description and Uses

2-hexyl-4-Pentynoic acid is a derivative of valproic acid , an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC₅₀ = 13 μM) than valproic acid (IC₅₀ = 398 μM). 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 μM. It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 μM.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xn
• Risk Statements: 22
• HS Code: 2916.19.3000