Home Categories Biochemical Engineering Fmoc-12-Ado-OH
BD3185545

Fmoc-12-Ado-OH , 97% , 128917-74-8

Synonym(s):
12-(Fmoc-amino)dodecanoic acid

CAS NO.:128917-74-8

Empirical Formula: C27H35NO4

Molecular Weight: 437.57

MDL number: MFCD00235888

Pack Size Price Stock Quantity
250mg RMB100.00 In Stock
1g RMB250.40 In Stock
5g RMB760.00 In Stock
10g RMB1292.00 In Stock
25g RMB2441.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 102 °C
Boiling point: 628.8±28.0 °C(Predicted)
Density  1.119±0.06 g/cm3(Predicted)
storage temp.  2-8°C
pka 4.78±0.10(Predicted)
BRN  9593537

Description and Uses

Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic Acid has been used as a reactant for the preparation of pro-apoptotic peptide functionalized gold nanoparticles as a new anti-cancer strategy of damaging mitochondria.

Safety

Safety Statements  22-24/25
WGK Germany  3

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