BD2733545
(S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile , 98+% , 2227425-05-8
CAS NO.:2227425-05-8
Empirical Formula: C15H14ClF3N4O2
Molecular Weight: 374.75
MDL number:
EINECS: 604-604-1
Pack Size | Price | Stock | Quantity |
5mg | RMB728.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 599.2±50.0 °C(Predicted) |
Density | 1.57±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 1 mg/mL; DMSO: 1mg/mL; Ethanol: 10mg/mL; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL |
form | A crystalline solid |
pka | 11.78±0.40(Predicted) |
color | White to off-white |
Description and Uses
PF-06869206 is an orally bioavailable inhibitor of sodium-phosphate cotransporter 2a (NaPi2a; IC50 = 380 nM). It is selective for NaPi2a over NaPi2b, NaPi2c, PiT-1, and PiT-2 (IC50s = >25 μM).
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |