Home Categories (S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
BD2733545

(S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile , 98+% , 2227425-05-8

CAS NO.:2227425-05-8

Empirical Formula: C15H14ClF3N4O2

Molecular Weight: 374.75

MDL number:

EINECS: 604-604-1

Pack Size Price Stock Quantity
5mg RMB728.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 599.2±50.0 °C(Predicted)
Density  1.57±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: 1 mg/mL; DMSO: 1mg/mL; Ethanol: 10mg/mL; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
form  A crystalline solid
pka 11.78±0.40(Predicted)
color  White to off-white

Description and Uses

PF-06869206 is an orally bioavailable inhibitor of sodium-phosphate cotransporter 2a (NaPi2a; IC50 = 380 nM). It is selective for NaPi2a over NaPi2b, NaPi2c, PiT-1, and PiT-2 (IC50s = >25 μM).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

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