Home Categories Biochemical Engineering 8-Hydroxyquinoline-5-carboxylicacid
BD2706645

8-Hydroxyquinoline-5-carboxylicacid , 99% , 5852-78-8

Synonym(s):
5-Carboxy-8-hydroxyquinoline;8-Hydroxy-5-quinolinecarboxylic acid;JHDM Inhibitor I, Histone Lysine Demethylase Inhibitor II, 5-carboxy-8HQ, IOX1;JMJD2 Inhibitor, 5-carboxy-8HQ - CAS 5852-78-8 - Calbiochem

CAS NO.:5852-78-8

Empirical Formula: C10H7NO3

Molecular Weight: 189.17

MDL number: MFCD18417145

Pack Size Price Stock Quantity
1g RMB5279.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 301 °C (decomp)
Boiling point: 464.5±30.0 °C(Predicted)
Density  1.480±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: soluble10mg/mL, clear
pka 1.82±0.10(Predicted)
form  powder
color  white to brown
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey JGRPKOGHYBAVMW-UHFFFAOYSA-N

Description and Uses

IOX 1 (5852-78-8) inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively.1?A broad spectrum 2-oxoglutarate oxygenase inhibitor, IOX 1 may be used to study hypoxic signaling.1?Cell permeable

8-Hydroxyquinoline-5-carboxylic Acid is an inhibitor of KDM2/7 histone demethylase. 8-Hydroxyquinoline-5-carboxylic acid has also shown potential to be used as a regulator of plant growth.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P261-P271-P280
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  2933499090

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