tert-Butyl(8-aminooctyl)carbamate , 97% , 88829-82-7

CAS NO.：88829-82-7

Empirical Formula: C13H28N2O2

Molecular Weight: 244.37

MDL number: MFCD02094499

PRODUCT Properties

• Boiling point: 356.3±25.0 °C(Predicted)
• Density: 0.942±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: Chloroform, Methanol
• form: Solid
• pka: 12.94±0.46(Predicted)
• color: Off-White

Description and Uses

tert-butyl (8-aminooctyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Hazard Note: Irritant
• HS Code: 2921290090