PRODUCT Properties
| Melting point: | -2℃ |
| Boiling point: | 56-60 °C(Press: 13 Torr) |
| Density | 0.85 g/mL at 25 °C(lit.) |
| storage temp. | Sealed in dry,2-8°C |
| pka | pK1:11.24(+1) (25°C,μ=0.5) |
| form | liquid |
| color | , clear colorless to yellow-green |
| CAS DataBase Reference | 3238-60-6(CAS DataBase Reference) |
Description and Uses
Coniine is present in all parts of the plantpoison hemlock (Conium maculatum). It isthe first alkaloid to be synthesized and structure determined. Because of its high toxicity,its clinical application is very limited.
Safety
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H226-H301-H311-H331-H351 |
| Precautionary statements | P201-P202-P210-P233-P240-P241-P242-P243-P260-P264-P270-P271-P280-P281-P301+P310-P302+P352-P303+P361+P353-P304+P340-P308+P313-P311-P312-P321-P322-P330-P361-P363-P370+P378-P403+P233-P403+P235-P405-P501 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-40 |
| Safety Statements | 22-36/37/39-45 |
| RIDADR | UN 2810 6.1/PG 2 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
| Toxicity | Piperidine alkaloid obtained from poison hemlock, Conium maculatum. Alkaline, steam volatile liquid (b.p. 167_x0003_C), mousy odor. Darkens and polymerizes in air. It can be reduced at high temperature with HI to n-octane and oxidized to pyridine-1-carboxylic acid. The hydrochloride is used as an antispasmodic. |
