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BD2017548

Ceftriaxone , 98+% , 73384-59-5

CAS NO.:73384-59-5

Empirical Formula: C18H18N8O7S3

Molecular Weight: 554.58

MDL number: MFCD00865013

EINECS: 277-405-6

Pack Size Price Stock Quantity
250mg RMB271.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 155 °C
Density  1.96±0.1 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka pKa –3.2±0.6 (Uncertain);–1.8±0.2 (Uncertain);2.57±0.50 (Uncertain);2.90±0.50 (Uncertain);8.03±0.40 (Uncertain)
color  Off-White to Pale Yellow
Stability: Hygroscopic
CAS DataBase Reference 73384-59-5(CAS DataBase Reference)
EPA Substance Registry System Ceftriaxone (73384-59-5)

Description and Uses

Ceftriaxone has the same C-7 side-chain moiety as cefotaxime and ceftizoxime, but the C-3 side chain consists of a metabolically stable and activating thiotriazinedione in place of the normal acetyl group. The C-3 side chain is sufficiently acidic that at normal pH, it forms an enolic sodium salt; thus, the commercial product is a disodium salt.

This drug has a broad spectrum of antimicrobial action that includes the majority of the clinically significant microorganisms: Gram-positive, Gram-negative, aerobic, anaerobic, and blue-pus bacillus. It is resistant with respect to most beta-lactamases of Gram-positive and Gram-negative bacteria.
It is used for peritonitis, sepsis, meningitis, cholangitis, empyema of the gall bladder, pneumonia, lung abscesses, pyelonephritis, infections of the bones, joints, skin, soft tissues, abdominal and gynecological infections, and for infected wounds and burns. The main synonym of this drug is rocefin.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H317-H334-H319-H335
Precautionary statements  P261-P285-P304+P341-P342+P311-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  22-24-37-45
HS Code  29349990

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