1,2,3,6-Tetrahydropyridine-4-carboxylicacid , 98% , 64603-90-3
Synonym(s):
1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride
| Pack Size | Price | Stock | Quantity |
| 1g | RMB3858.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 220 °C |
| Boiling point: | 280.8±35.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| RTECS | US5908286 |
| storage temp. | Store at RT |
| solubility | H2O: refrigerate if not used immediately.soluble |
| form | solid |
| pka | pK1:9.07 (25°C) |
| color | white |
| Water Solubility | Soluble in water |
Description and Uses
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca catechu. It is optically inactive and yields crystalline salts: the hydrochloride, m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C. The alkaloid is faintly acid to litmus and on methylation gives the N-methyl derivative which, on more vigorous methylation yields the dimethyl compound giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust, it yields products with the characteristic pyrrole reaction.
A GABAA receptor agonist. Anticonvulsant; antiepileptic.
Safety
| Symbol(GHS) |  GHS07 |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
