tert-Butyl 3-(2-(2-hydroxyethoxy)ethoxy)propanoate , 95% , 133803-81-3
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB120.80 | In Stock |
|
| 1g | RMB251.20 | In Stock |
|
| 5g | RMB896.80 | In Stock |
|
| 10g | RMB1513.60 | In Stock |
|
| 25g | RMB3044.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 321.8±22.0 °C(Predicted) |
| Density | 1.046±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in DMSO |
| form | clear liquid |
| pka | 14.36±0.10(Predicted) |
| color | Colorless to Almost colorless |
Description and Uses
Hydroxy-PEG2-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Hydroxy-PEG2-(CH2)2-Boc is an ADC linker for the synthesis of antibody drug conjugates (ADC), Hydroxy-PEG2-(CH2)2-Boc is derived from patent WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc can also be used as a PROTAC linker for PROTAC synthesis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2918999090 |
