Fmoc-7-Ahp-OH , 98% , 127582-76-7

CAS NO.：127582-76-7

Empirical Formula: C22H25NO4

Molecular Weight: 367.44

MDL number: MFCD01861353

PRODUCT Properties

• Boiling point: 590.0±33.0 °C(Predicted)
• Density: 1.191±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,2-8°C
• pka: 4.77±0.10(Predicted)
• form: Powder
• color: White
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 127582-76-7(CAS DataBase Reference)

Description and Uses

Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280-P305+P351+P338
• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 2924297099