5-(Piperazin-1-yl)pyridin-2-amine , 98% , 1082876-26-3

CAS NO.：1082876-26-3

Empirical Formula: C9H14N4

Molecular Weight: 178.23

MDL number:

PRODUCT Properties

• Boiling point: 401.7±40.0 °C(Predicted)
• Density: 1.163±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 8.67±0.10(Predicted)
• form: Solid
• color: Pale Brown to Light Brown

Description and Uses

5-?(1-?Piperazinyl)?-?2-?pyridinamine is a reagent used in the synthesis of anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2933998090