Aurothioglucose , 98+% , 12192-57-3
Synonym(s):
GGT;GGT 1;Gold thioglucose;GTG;Solganal
CAS NO.：12192-57-3
Empirical Formula: C6H11AuO5S
Molecular Weight: 392.18
MDL number: MFCD00056080
EINECS: 235-365-7
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1721.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >107oC (dec.) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear |
| form | powder |
| color | white to beige |
| Merck | 13,887 |
| Stability: | Hygroscopic, Light Sensitive |
| IARC | 3 (Vol. 13, Sup 7) 1987 |
| EPA Substance Registry System | Aurothioglucose (12192-57-3) |
Description and Uses
Aurothioglucose is highly water soluble, and its aqueous solutions decompose on long standing. It therefore is available as a suspension in sesame oil. Gold content is approximately 50%. Following IM injection, it is highly protein bound (95%), and peak plasma levels are achieved within 2 to 6 hours. Following a single 50-mg dose, the biological half-life ranges from 3 to 27 days, but following successive weekly doses, the half-life increases to 14 to 40 days after the third dose. The therapeutic effect does not correlate with serum plasma gold levels but appears to depend on total accumulated gold. Aurothioglucose is indicated for the adjunctive treatment of adult and juvenile rheumatoid arthritis.
Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317-H412 |
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37-45 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2843300000 |
| Hazardous Substances Data | 12192-57-3(Hazardous Substances Data) |
| Toxicity | LD50 intravenous in chicken: 1gm/kg |
