CefditorenPivoxil , 98% , 117467-28-4
CAS NO.:117467-28-4
Empirical Formula: C25H28N6O7S3
Molecular Weight: 620.72
MDL number: MFCD00933166
EINECS: 688-157-7
Pack Size | Price | Stock | Quantity |
1g | RMB84.00 | In Stock |
|
5g | RMB296.80 | In Stock |
|
25g | RMB1080.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 207-209°C |
alpha | D20 -48.5° (c = 0.5 in methanol) |
Density | 1.55±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | 8.08±0.60(Predicted) |
color | Off-White to Pale Yellow |
Merck | 14,1921 |
Description and Uses
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren. Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively. Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
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Safety
Symbol(GHS) | GHS08 |
Signal word | Danger |
Hazard statements | H317-H334 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
RTECS | XI0367800 |
HS Code | 2941.90.3000 |