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A3893856

Cefotetan , 96% , 69712-56-7

CAS NO.:69712-56-7

Empirical Formula: C17H17N7O8S4

Molecular Weight: 575.62

MDL number: MFCD00864983

EINECS: 274-093-3

Pack Size Price Stock Quantity
10mg RMB135.20 In Stock
50mg RMB399.20 In Stock
250mg RMB1199.20 In Stock
1g RMB3839.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 173-178°C (dec.)
Density  1.5157 (rough estimate)
refractive index  1.7400 (estimate)
storage temp.  Store at 0-5°C
solubility  DMSO (Slightly), Methanol (Very Slightly)
form  Solid
pka 1.69±0.41(Predicted)
color  White to Off-White
Merck  14,1934
Stability: Hygroscopic
InChIKey SRZNHPXWXCNNDU-IXOPCIAXSA-N
CAS DataBase Reference 69712-56-7(CAS DataBase Reference)

Description and Uses

Cefotetan is comparatively stable, lasting for approximately 24 hours at room temperature when reconstituted. Slight yellowing and slight darkening produce materials that are still acceptable for therapy. Cefotetan is chemically incompatible with tetracycline, aminoglycosides, and with heparin, often forming precipitates with them. With respect to its molecular mode of action, it has a special affinity for PBP-3 of Gram-negative bacteria, consequently producing filamentous forms. It also binds well with PBP-1A and -1B,therefore leading to cell lysis and death. Whereas it is stable to a wide range of β-lactamases, it also is a potent inducer in some bacteria.

Cefotetan disodium is an antibiotic related to Cephalosporin, used in the treatment of bacterial infections.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
RTECS  XI0330800
HS Code  2941906000

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