Cefotetan , 96% , 69712-56-7
CAS NO.:69712-56-7
Empirical Formula: C17H17N7O8S4
Molecular Weight: 575.62
MDL number: MFCD00864983
EINECS: 274-093-3
Pack Size | Price | Stock | Quantity |
10mg | RMB135.20 | In Stock |
|
50mg | RMB399.20 | In Stock |
|
250mg | RMB1199.20 | In Stock |
|
1g | RMB3839.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 173-178°C (dec.) |
Density | 1.5157 (rough estimate) |
refractive index | 1.7400 (estimate) |
storage temp. | Store at 0-5°C |
solubility | DMSO (Slightly), Methanol (Very Slightly) |
pka | 1.69±0.41(Predicted) |
form | Solid |
color | White to Off-White |
Merck | 14,1934 |
Stability: | Hygroscopic |
InChIKey | SRZNHPXWXCNNDU-IXOPCIAXSA-N |
Description and Uses
Cefotetan is comparatively stable, lasting for approximately 24 hours at room temperature when reconstituted. Slight yellowing and slight darkening produce materials that are still acceptable for therapy. Cefotetan is chemically incompatible with tetracycline, aminoglycosides, and with heparin, often forming precipitates with them. With respect to its molecular mode of action, it has a special affinity for PBP-3 of Gram-negative bacteria, consequently producing filamentous forms. It also binds well with PBP-1A and -1B,therefore leading to cell lysis and death. Whereas it is stable to a wide range of β-lactamases, it also is a potent inducer in some bacteria.
Cefotetan disodium is an antibiotic related to Cephalosporin, used in the treatment of bacterial infections.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
RTECS | XI0330800 |
HS Code | 2941906000 |