3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one , 99+% , 189954-96-9
CAS NO.：189954-96-9
Empirical Formula: C17H20O5S
Molecular Weight: 336.4
MDL number: MFCD09837800
EINECS: 200-001-2
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB205.60 | In Stock |
|
| 250mg | RMB308.00 | In Stock |
|
| 1g | RMB646.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 78-80°C |
| Boiling point: | 563.9±50.0 °C(Predicted) |
| Density | 1.31 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3 |
| InChIKey | FULAPETWGIGNMT-UHFFFAOYSA-N |
| SMILES | O1C(C)(C)C(C2=CC=C(S(C)(=O)=O)C=C2)=C(OCC2CC2)C1=O |
Description and Uses
Firocoxib is a selective inhibitor of COX-2 (IC50s = 0.13 and 7.5 μM for COX-2 and COX-1, respectively, in isolated cat blood). It inhibits LPS-induced production of prostaglandin E2 (PGE2; ) in isolated dog, horse, and cat whole blood ex vivo. Firocoxib decreases lameness, induces analgesia, and improves range of motion in dogs and horses with osteoarthritis when administered at doses of 5 and 0.1 mg/kg per day, respectively. Formulations containing firocoxib have been used in dogs and horses with osteoarthritis.
A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H412-H361-H373 |
| Precautionary statements | P273-P501-P260-P314-P501-P201-P202-P281-P308+P313-P405-P501 |
