(S)-2-(Methoxydiphenylmethyl)pyrrolidine , 95% , 118971-03-2

CAS NO.：118971-03-2

Empirical Formula: C18H21NO

Molecular Weight: 267.37

MDL number: MFCD09750440

PRODUCT Properties

• Boiling point: 368.7±32.0 °C(Predicted)
• Density: 1.070±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: soluble in Dichloromethane, Ethyl Acetate
• pka: 10.09±0.10(Predicted)
• form: Oil
• color: Yellow

Description and Uses

(S)-2-(Methoxydiphenylmethyl)pyrrolidine is a diphenylprolinol methyl ether, which can be used as a catalyst to synthesize:

• Enantioselective ketones via intermolecular asymmetric Michael addition of aldehydes to nonactivated enones.
• Stereoselective chiral bipyrazolidin-3-one derivatives by dipolar cycloaddition reaction of azomethine imines with α, β-unsaturated aldehydes.
• Enantioenriched spiro nitrogen heterocycles via asymmetric nucleophilic epoxidation of α-ylideneoxindole esters.
• Optically active secondary alcohols by asymmetric addition of Et₂Zn to various aldehydes.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22
• WGK Germany: 3