1-(tert-Butoxycarbonyl)azetidine-2-carboxylic acid , 95% , 159749-28-7
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB36.00 | In Stock |
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| 1g | RMB81.60 | In Stock |
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| 5g | RMB376.00 | In Stock |
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| 10g | RMB632.80 | In Stock |
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| 25g | RMB1472.80 | In Stock |
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| 100g | RMB5608.00 | In Stock |
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| others | Enquire |
PRODUCT Properties
| Boiling point: | 321.0±35.0 °C(Predicted) |
| Density | 1.246±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.01±0.20(Predicted) |
| form | solid |
| color | Pale yellow |
Description and Uses
Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester (ADCBT) is a pyrrolidinyl nicotinic acetylcholine receptor agonist. ADCBT has been shown to have affinity values for neuronal nicotinic acetylcholine receptors that are significantly higher than those of nicotine. It has been shown to be regioselective in the sense that it binds preferentially to the alpha4beta2 subtype of the nicotinic acetylcholine receptor, which is present in both peripheral and central neurons. It also has a high affinity for the acetylcholine binding site at the neuromuscular junction. ADCBT has been shown to have analgesic effects in animal studies.
Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester, is an useful intermediate in the synthesis of pharmaceutical compounds including inhibitors and receptor Antagonists. It can be used in the synthesis of polypeptides.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi,N |
| Risk Statements | 36/37/38-50 |
| Safety Statements | 26-36-61-24/25 |
| RIDADR | UN3077 |
| WGK Germany | 3 |
| HS Code | 29339900 |
