Salbutamol Solution , 100mg/L , 18559-94-9

Synonym(s):
α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol;Albuterol;Salbutamol

CAS NO.：18559-94-9

Empirical Formula: C13H21NO3

Molecular Weight: 239.32

MDL number: MFCD00869868

EINECS: 242-424-0

PRODUCT Properties

• Melting point: 157-160℃
• Boiling point: 381.97°C (rough estimate)
• Density: 1.0700 (rough estimate)
• refractive index: 1.4800 (estimate)
• storage temp.: 2-8°C
• solubility: Sparingly soluble in water, soluble in ethanol (96 per cent).
• pka: pKa 9.07(H2O t = 25.0±0.05 I = 0.10) (Uncertain);10.37(H2O t = 25.0±0.05 I = 0.10) (Uncertain)
• form: Solid
• color: White
• Water Solubility: 17.95g/L(25 ºC)
• Merck: 13,215
• BRN: 6405698
• BCS Class: 3
• Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents.
• InChIKey: NDAUXUAQIAJITI-UHFFFAOYSA-N
• LogP: 0.64
• CAS DataBase Reference: 18559-94-9(CAS DataBase Reference)
• EPA Substance Registry System: 1,3-Benzenedimethanol, .alpha.1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy- (18559-94-9)

Description and Uses

Albuterol is a β2-adrenergic sympathomimetic amine with pharmacological similarities to terbutaline. It has almost no effect on β1-adrenoreceptors of the heart. It has expressed broncholytic effects—prevention or relief of bronchi spasms, lowering respiratory tract resistance, and increasing the vital capacity of the lungs.

Albuterol is widely used for severe and chronic bronchial asthma and other illnesses of the respiratory tract that result in a spastic condition of the bronchi.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H317-H319-H412
• Precautionary statements: P261-P273-P280-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn,T,F
• Risk Statements: 22-39/23/24/25-23/24/25-11
• Safety Statements: 36-45-36/37-16-7
• RIDADR: 3249
• WGK Germany: 3
• RTECS: ZE4400000
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 2922504500
• Hazardous Substances Data: 18559-94-9(Hazardous Substances Data)