Salbutamol sulfate , ≧95% , 51022-70-9
Synonym(s):
α-([t-Butylamino]methyl)-4-hydroxy-m-xylene-α,α′-diol;α1-[(tert-Butylamino)methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate salt;Albuterol;Albuterol sulfate;Salbutamol hemisulfate salt
CAS NO.:51022-70-9
Empirical Formula: C13H23NO7S
Molecular Weight: 337.39
MDL number: MFCD00055200
EINECS: 256-916-8
Pack Size | Price | Stock | Quantity |
100MG | RMB31.20 | In Stock |
|
1g | RMB200.00 | In Stock |
|
5g | RMB703.20 | In Stock |
|
25g | RMB2399.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 180 °C |
Flash point: | 250 °C |
storage temp. | 2-8°C |
solubility | 1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green |
form | Solid |
color | White |
Water Solubility | Soluble in water and 1M sodium hydroxide (50 mg/ml). |
Merck | 216 |
BCS Class | 1 |
InChI | InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4) |
InChIKey | OVICLFZZVQVVFT-UHFFFAOYSA-N |
SMILES | CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O |
CAS DataBase Reference | 51022-70-9(CAS DataBase Reference) |
Description and Uses
Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.
Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications.
Safety
Symbol(GHS) | GHS07,GHS08 |
Signal word | Warning |
Hazard statements | H317-H351-H361fd |
Precautionary statements | P202-P261-P272-P280-P302+P352-P308+P313 |
Hazard Codes | Xn,Xi |
Risk Statements | 43-22 |
Safety Statements | 36/37-36 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | ZE4400000 |
HS Code | 29225090 |