A8361012
VcMMAE , 98% , 646502-53-6
CAS NO.：646502-53-6
Empirical Formula: C68H105N11O15
Molecular Weight: 1316.63
MDL number: MFCD25372036
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB479.20 | In Stock |
|
| 5mg | RMB1407.20 | In Stock |
|
| 10mg | RMB2239.20 | In Stock |
|
| 25mg | RMB3919.20 | In Stock |
|
| 50mg | RMB6319.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 1347.6±65.0 °C(Predicted) |
| Density | 1.196±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in DMSO, DCM, DMF |
| form | A solid |
| pka | 13.29±0.70(Predicted) |
| color | White to off-white |
| InChIKey | NLMBVBUNULOTNS-NNNQBTKHNA-N |
Description and Uses
MC-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a thio reactive maleimidocaproyl (MC) group, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.
Vedotin is an ultra-high-affinity small organic ligand of fibroblast activation protein used for tumor-targeting applications
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
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