Valeric acid , >99%(GC) , 109-52-4
Synonym(s):
n-Valeric acid;Pentanoic acid;Valeric acid;Valproic acid impurity A (PhEur)
CAS NO.：109-52-4
Empirical Formula: C5H10O2
Molecular Weight: 102.13
MDL number: MFCD00004413
EINECS: 203-677-2
PRODUCT Properties
| Melting point: | −20-−18 °C(lit.) |
| Boiling point: | 110-111 °C10 mm Hg(lit.) |
| Density | 0.939 g/mL at 25 °C(lit.) |
| vapor density | 3.5 (vs air) |
| vapor pressure | 0.15 mm Hg ( 20 °C) |
| refractive index | n |
| FEMA | 3101 | VALERIC ACID |
| Flash point: | 192 °F |
| storage temp. | Store below +30°C. |
| solubility | 40g/l |
| form | Liquid |
| pka | 4.84(at 25℃) |
| color | Clear colorless to pale yellow |
| PH | 3.95(1 mM solution);3.43(10 mM solution);2.92(100 mM solution); |
| Odor | at 1.00 % in propylene glycol. sickening putrid acidic sweaty rancid |
| Odor Type | cheesy |
| Odor Threshold | 0.000037ppm |
| explosive limit | 1.8-7.3%(V) |
| Water Solubility | 40 g/L (20 ºC) |
| Merck | 14,9904 |
| JECFA Number | 90 |
| BRN | 969454 |
| Dielectric constant | 2.7（20℃） |
| LogP | 1.8 at 25℃ |
| CAS DataBase Reference | 109-52-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Pentanoic acid(109-52-4) |
| EPA Substance Registry System | Valeric acid (109-52-4) |
Description and Uses
Valeric acid, or pentanoic acid, is a straight - chain alkyl carboxylic acid with the chemical formula C5H10O2. Like other lowmolecular- weight carboxylic acids, it has a very unpleasant odor. It is found naturally in the perennial flowering plant valerian (Valeriana officinalis), from which it gets its name. Its primary use is in the synthesis of its esters. Volatile esters of valeric acid tend to have pleasant odors and are used in perfumes and cosmetics. Ethyl valerate and pentyl valerate are used as food additives because of their fruity flavors.
Valeric acid appears similar in structure to GHB and the neurotransmitter GABA in that it is a short-chain carboxylic acid, although it lacks the alcohol and amine functional groups that contribute to the biological activities of GHB and GABA, respectively. It differs from valproic acid simply by lacking a 3- carbon side - chain.
valeric acid is obtained from valerian extract, which is considered skin conditioning.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314-H412 |
| Precautionary statements | P273-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| Hazard Codes | C |
| Risk Statements | 34-52/53 |
| Safety Statements | 26-36-45-61 |
| RIDADR | UN 3265 8/PG 3 |
| WGK Germany | 1 |
| RTECS | YV6100000 |
| F | 13 |
| Autoignition Temperature | 707 °F |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29156090 |
| Hazardous Substances Data | 109-52-4(Hazardous Substances Data) |
| Toxicity | LD50 i.v. in mice: 1290 ±53 mg/kg (Or, Wretlind) |
