A7927112
3,3',5-Triiodo-L-thyronine , >98.0%(HPLC) , 6893-02-3
Synonym(s):
Liothyronine;Reverse T3;rT(3);T3;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L -tyrosine
CAS NO.：6893-02-3
Empirical Formula: C15H12I3NO4
Molecular Weight: 650.97
MDL number: MFCD00002593
EINECS: 229-999-3
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB108.80 | In Stock |
|
| 1G | RMB272.00 | In Stock |
|
| 5G | RMB1006.40 | In Stock |
|
| 25g | RMB4399.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 234-238 °C(lit.) |
| alpha | 23 º (c=2 in ethanol) |
| Boiling point: | 232°C (rough estimate) |
| Density | 2.2155 (estimate) |
| Flash point: | 9°C |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly) |
| form | powder |
| pka | pKa 8.5 (Uncertain);8.4 (Uncertain);8.45 (Uncertain) |
| color | Off-white to pale yellow |
| optical activity | [α]25/D +23.0°, c = 2 in 1 N HCl: ethanol, 1:2 |
| Water Solubility | Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies. |
| Sensitive | Light Sensitive |
| Merck | 14,5510 |
| BRN | 2710227 |
| Stability: | Light Sensitive |
Description and Uses
Crystalline T3 (liothyronine sodium, Cytomel) has a rapid onset and short duration of action. It is the therapy of choice when it is desirable to have rapid onset or cessation of activity, such as in patients with heart disease.
3,3’,5-Triiodo-L-thyronine (Levothyroxine EP Impurity A) is one of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Danger |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xn,Xi,T,F |
| Risk Statements | 20/21/22-36/37/38-39/23/24/25-23/24/25-11 |
| Safety Statements | 36-26-36/37/39-45-36/37-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| RTECS | AY6750000 |
| F | 8 |
| HS Code | 29225090 |
| Toxicity | LDLo oral in rat: 7500mg/kg |
