A7838212
Tetrabenazine , 98% , 58-46-8
Synonym(s):
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2H-benzo[a]quinolizin-2-one;Tetrabenazine, TBZ - CAS 58-46-8 - Calbiochem;VMAT2 Inhibitor, Xenazine
CAS NO.:58-46-8
Empirical Formula: C19H27NO3
Molecular Weight: 317.42
MDL number: MFCD00042740
EINECS: 200-383-6
Pack Size | Price | Stock | Quantity |
250MG | RMB303.20 | In Stock |
|
1G | RMB594.40 | In Stock |
|
5g | RMB2374.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 128-130?C |
Boiling point: | 456.71°C (rough estimate) |
Density | 1.12 |
refractive index | 1.5180 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO: >10mg/mL |
pka | 6.46±0.40(Predicted) |
form | solid |
color | White |
Merck | 14,9182 |
BRN | 40090 |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week. |
InChIKey | MKJIEFSOBYUXJB-UHFFFAOYSA-N |
Description and Uses
Tetrabenazine (58-46-8) is a potent inhibitor of the vesicular monoamine transporter (VMAT), IC50=3.2 nM with selectivity for VMAT2 over VMAT1. Promotes late stage differentiation of Pdx1-positive pancreatic progenitor cells into Neurog3-positive endocrine precursors.
Dopamine depleting agent. An antidyskinetic; antipsychotic.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P501 |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 24/25 |
RIDADR | 3249 |
WGK Germany | 3 |
RTECS | DK2275000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29339900 |
Hazardous Substances Data | 58-46-8(Hazardous Substances Data) |