A7838212
Tetrabenazine , 98% , 58-46-8
Synonym(s):
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2H-benzo[a]quinolizin-2-one;Tetrabenazine, TBZ - CAS 58-46-8 - Calbiochem;VMAT2 Inhibitor, Xenazine
CAS NO.：58-46-8
Empirical Formula: C19H27NO3
Molecular Weight: 317.42
MDL number: MFCD00042740
EINECS: 200-383-6
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB303.20 | In Stock |
|
| 1G | RMB594.40 | In Stock |
|
| 5g | RMB2374.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 128-130?C |
| Boiling point: | 456.71°C (rough estimate) |
| Density | 1.12 |
| refractive index | 1.5180 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: >10mg/mL |
| pka | 6.46±0.40(Predicted) |
| form | solid |
| color | White |
| Merck | 14,9182 |
| BRN | 40090 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week. |
| InChIKey | MKJIEFSOBYUXJB-UHFFFAOYSA-N |
Description and Uses
Tetrabenazine (58-46-8) is a potent inhibitor of the vesicular monoamine transporter (VMAT), IC50=3.2 nM with selectivity for VMAT2 over VMAT1. Promotes late stage differentiation of Pdx1-positive pancreatic progenitor cells into Neurog3-positive endocrine precursors.
Dopamine depleting agent. An antidyskinetic; antipsychotic.
