Trospium chloride , ≥99% , 10405-02-4

CAS NO.：10405-02-4

Empirical Formula: C25H30ClNO3

Molecular Weight: 427.96

MDL number: MFCD00865254

EINECS: 233-875-4

PRODUCT Properties

• Melting point: 266-268°C
• storage temp.: Inert atmosphere,2-8°C
• solubility: Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride.
• form: Solid
• color: White to Off-White
• Merck: 14,9786
• InChIKey: RVCSYOQWLPPAOA-QKYUOBHYSA-M
• SMILES: [N+]12(CCCC1)[C@@]1([H])CC[C@]2([H])C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1C=CC=CC=1.[Cl-] |&1:5,9,12,r|

Description and Uses

Trospium chloride (Sanctura) is an antimuscarinic that has been used in Europe for the management of OAB symptoms for over 30 years.Trospium chloride's chemical structure is such that it is unlikely to penetrate the brain and thus does not appear to affect cognitive function. Trospium chloride is usually administered orally twice a day in 20mg. Trospium chloride should be taken 1 hour before meals or on an empty stomach. It is not well absorbed if taken with food.An advantage of this medication is that it has little potential interaction with other medications.

Labeled Trospium, intended for use as an internal standard for the quantification of Trospium by GC- or LC-mass spectrometry.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• RTECS: WH1424000
• HS Code: 2939800000
• Toxicity: Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler)