A7819412
Tolfenamic Acid , ≥98% , 13710-19-5
Synonym(s):
2 (3-Chloro-2-methylanilino)benzoic acid;2-([3-Chloro-2-methylphenyl]amino)benzoic acid;Tolfenamic acid
CAS NO.：13710-19-5
Empirical Formula: C14H12ClNO2
Molecular Weight: 261.7
MDL number: MFCD00133865
EINECS: 237-264-3
| Pack Size | Price | Stock | Quantity |
| 5G | RMB72.80 | In Stock |
|
| 25G | RMB220.00 | In Stock |
|
| 100g | RMB746.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 210-214°C |
| Boiling point: | 405.4±40.0 °C(Predicted) |
| Density | 1.2037 (rough estimate) |
| refractive index | 1.5270 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides. |
| form | Solid |
| pka | 3.66±0.36(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in water (slightly), acetone (~10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (~10 mg/ml) and ethanol (50 mg/ml). |
| Merck | 14,9513 |
| InChIKey | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
Description and Uses
Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 μM.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P405-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CB2687500 |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29224919 |
