Tropisetron Hydrochloride , ≥98.0% , 105826-92-4

Synonym(s):
1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride;3-Tropanylindole-3-carboxylate monohydrochloride;ICS-205,930;Navoban;Tropisetron monohydrochloride

CAS NO.：105826-92-4

Empirical Formula: C17H21ClN2O2

Molecular Weight: 320.81

MDL number: MFCD02313825

EINECS: 630-417-9

PRODUCT Properties

• Melting point: 283-285°C
• RTECS: NL6012520
• storage temp.: 2-8°C
• solubility: H2O: >10mg/mL
• form: solid
• color: White to Light yellow
• Water Solubility: Soluble in water
• Merck: 14,9783
• InChI: InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?
• InChIKey: ZAOQBEAHJFSJLY-NBVCILBMNA-N
• SMILES: C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r|

Description and Uses

A selective 5-HT3 serotonin receptor antagonist

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P264-P270-P301+P310a-P321-P405-P501a
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29399990
• Toxicity: mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998.