3-Nitro-L-tyrosine , 2mMinDMSO , 621-44-3

CAS NO.：621-44-3

Empirical Formula: C9H10N2O5

Molecular Weight: 226.19

MDL number: MFCD00007123

EINECS: 210-688-6

PRODUCT Properties

• Melting point: 233-235 °C (dec.) (lit.)
• alpha: 4 º (c=1, 1N HCl)
• Boiling point: 367.79°C (rough estimate)
• Density: 1.4160 (rough estimate)
• refractive index: 1.5373 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Aqueous Acid (Slightly), Water
• form: crystalline
• pka: 2.17±0.20(Predicted)
• color: yellow to green
• Water Solubility: insoluble
• BRN: 2813157
• CAS DataBase Reference: 621-44-3(CAS DataBase Reference)

Description and Uses

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P302+P352-P362+P364
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 24/25-37/39-26-36
• WGK Germany: 3
• HS Code: 29225090