O4I1 , 10mMinDMSO , 175135-47-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 424.5±30.0 °C(Predicted) |
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly |
| form | A crystalline solid |
| color | Light yellow to yellow |
Description and Uses
O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.
O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P231-P222-P261-P305+P351+P338-P403+P233-P422-P501 |
| HS Code | 2926907090 |
