A7734458
Itraconazole , 2mMinDMSO , 84625-61-6
Synonym(s):
;Itraconazole;Oriconazole;Sporanox
CAS NO.:84625-61-6
Empirical Formula: C35H38Cl2N8O4
Molecular Weight: 705.63
MDL number: MFCD08064196
EINECS: 617-596-9
Pack Size | Price | Stock | Quantity |
1ml | RMB159.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 166°C |
alpha | -0.1~+0.1°(D/20℃)(c=10,CH2Cl2) |
Boiling point: | 850.0±75.0 °C(Predicted) |
Density | 1.27 g/cm3 |
Flash point: | >110°(230°F) |
storage temp. | 2-8°C |
solubility | chloroform: 50 mg/mL, clear, colorless |
form | White powder |
pka | 3.7(at 25℃) |
color | white |
Water Solubility | Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol |
Merck | 14,5245 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | VHVPQPYKVGDNFY-UHFFFAOYSA-N |
Description and Uses
Itraconazole is an orally-active triazole antifungal indicated for use in the treatment of dermal, vaginal and systemic mycoses. In immunocompromised and AIDS patients, itraconazole has been shown to significantly reduce the incidence of relapses of cryptococcal meningitis.
A traizole antifungal agent
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
Hazard Codes | Xi,Xn,T,F |
Risk Statements | 36/37/38-36/38-22-39/23/24/25-23/24/25-11 |
Safety Statements | 22-26-36-45-36/37-16 |
RIDADR | UN 3286 8(6.1)(3) / PGII |
WGK Germany | 3 |
RTECS | XZ5481000 |
HS Code | 2934990002 |
Toxicity | LD50 (14 day) in mice, rats, dogs (mg/kg): >320, >320, >200 orally (Van Cauteren) |