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A7734458

Itraconazole , 2mMinDMSO , 84625-61-6

Synonym(s):
;Itraconazole;Oriconazole;Sporanox

CAS NO.:84625-61-6

Empirical Formula: C35H38Cl2N8O4

Molecular Weight: 705.63

MDL number: MFCD08064196

EINECS: 617-596-9

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 166°C
alpha  -0.1~+0.1°(D/20℃)(c=10,CH2Cl2)
Boiling point: 850.0±75.0 °C(Predicted)
Density  1.27 g/cm3
Flash point: >110°(230°F)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear, colorless
form  White powder
pka 3.7(at 25℃)
color  white
Water Solubility  Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck  14,5245
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey VHVPQPYKVGDNFY-UHFFFAOYSA-N

Description and Uses

Itraconazole is an orally-active triazole antifungal indicated for use in the treatment of dermal, vaginal and systemic mycoses. In immunocompromised and AIDS patients, itraconazole has been shown to significantly reduce the incidence of relapses of cryptococcal meningitis.

A traizole antifungal agent

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn,T,F
Risk Statements  36/37/38-36/38-22-39/23/24/25-23/24/25-11
Safety Statements  22-26-36-45-36/37-16
RIDADR  UN 3286 8(6.1)(3) / PGII
WGK Germany  3
RTECS  XZ5481000
HS Code  2934990002
Toxicity LD50 (14 day) in mice, rats, dogs (mg/kg): >320, >320, >200 orally (Van Cauteren)

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