Home Categories API Tetraethylthiuram disulfide
A7723612

Tetraethylthiuram disulfide , 97% , 97-77-8

Synonym(s):
Disulfiram;TETD;Tetraethylthiuram disulfide;DRAM;DRAM1

CAS NO.:97-77-8

Empirical Formula: C10H20N2S4

Molecular Weight: 296.54

MDL number: MFCD00009048

EINECS: 202-607-8

Pack Size Price Stock Quantity
25G RMB28.80 In Stock
100G RMB48.80 In Stock
250g RMB79.20 In Stock
500G RMB158.40 In Stock
2.5KG RMB668.80 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 69-71 °C (lit.)
Boiling point: 117°C
Density  1.27
vapor pressure  0Pa at 25℃
refractive index  1.5500 (estimate)
Flash point: 117°C/17mm
storage temp.  2-8°C
solubility  0.004g/l
pka 0.86±0.50(Predicted)
form  Crystals, Crystalline Powder or Granules
color  Light yellow
Odor lt. gray powd., sl. odor
Water Solubility  0.02 g/100 mL
Merck  14,3364
BRN  1712560
Exposure limits ACGIH: TWA 2 mg/m3
NIOSH: TWA 2 mg/m3
Stability: Stable. Incompatible with strong oxidants.
InChIKey AUZONCFQVSMFAP-UHFFFAOYSA-N
LogP 3.6 at 21℃
CAS DataBase Reference 97-77-8(CAS DataBase Reference)
NIST Chemistry Reference Disulfiram(97-77-8)
IARC 3 (Vol. 12, Sup 7) 1987
EPA Substance Registry System Disulfiram (97-77-8)

Description and Uses

Disulfiram was first synthesized in the 1800s to improve the manufacturing process of rubber. A physician working in a rubber factory plant first observed in 1937 that factory workers who were exposed to disulfiram were intolerant to ethanol. In the 1940s, two scientists rediscovered the disulfiram– ethanol effects while researching antiparasitic therapies. This finding eventually led to the approval of the medication to be used as an ethanol deterrent by the Food and Drug Administration in 1951.

Alcohol deterrent;Dopamine beta-hydroxylase inhibitor;For the treatment and management of chronic alcoholism.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H317-H373-H410
Precautionary statements  P273-P280-P301+P312+P330-P302+P352-P314
Hazard Codes  Xn,N
Risk Statements  22-43-48/22-50/53
Safety Statements  24-37-60-61
OEB B
OEL TWA: 2 mg/m3 [Precautions should be taken to avoid concurrent exposure to ethylene dibromide.]
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  JO1225000
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29303000
Hazardous Substances Data 97-77-8(Hazardous Substances Data)
Toxicity LD50 orally in rats: 8.6 g/kg (Child, Cramp)

RELATED PRODUCTS