Home Categories Chemical Reagents 2,2,2-Trichloroethanol
A7717612

2,2,2-Trichloroethanol , 98% , 115-20-8

Synonym(s):
ß,ß,ß-Trichloroethyl alcohol;2,2,2-Trichloroethanol;Trichloroethyl alcohol

CAS NO.:115-20-8

Empirical Formula: C2H3Cl3O

Molecular Weight: 149.4

MDL number: MFCD00004677

EINECS: 204-071-0

Pack Size Price Stock Quantity
5g RMB26.40 In Stock
25G RMB39.20 In Stock
100G RMB95.20 In Stock
500G RMB400.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 17.8 °C (lit.)
Boiling point: 152-154 °C (lit.)
Density  1.56 g/mL at 20 °C (lit.)
vapor density  5.16 (vs air)
vapor pressure  1 mm Hg ( 20 °C)
refractive index  n20/D 1.49(lit.)
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  83g/l
form  Liquid
pka 12.24(at 25℃)
color  Clear colorless to light yellow
Specific Gravity 1.560 (20/4℃)
Odor ethereal odor
PH 5-6 (H2O, 20℃)(saturated solution)
Water Solubility  Slightly soluble in water.
Sensitive  Hygroscopic
Merck  14,9638
BRN  1697495

Description and Uses

The 2,2,2-Trichloroethyl (TCE) moiety of 2,2,2-trichloroethanol is mainly used as a protecting group for acids, acetals and also phosphoryl groups of nucleotides. It can be easily cleaved by zinc reduction.
Some of its other application include:

  • Conversion of per-O-acetylated sugars to per-O-acetylated trichloroethyl derivatives.
  • Preparation of TCE ester of chlorosulfuric acid.
  • Preparation of 2,2,2-trichloroethyl acetimidate hydrochloride.

Safety

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318-H336
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-41-67
Safety Statements  26-39
RIDADR  1760
WGK Germany  1
RTECS  KM3850000
3-21
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29055910
Toxicity LDLo orl-rat: 500 mg/kg CRAAA7 17,258,38

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