Palonosetron , 10mMinDMSO , 135729-61-2
CAS NO.：135729-61-2
Empirical Formula: C19H24N2O
Molecular Weight: 296.41
MDL number:
EINECS: 1312995-182-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB236.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 87-88° |
| alpha | D -136° (c = 0.25 in chloroform) |
| Boiling point: | 470.4±45.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO |
| form | Powder |
| pka | 9.77±0.33(Predicted) |
Description and Uses
Palonosetron is a new generation 5-HT3 antagonist and It has hasgreater receptor-binding properties, which results in a much longer half-life than the previously described drugs. This selective and conformationally restricted 5-HT3 receptor antagonist was approved for the treatment of chemotherapy-induced nausea and vomiting. The drug was originally developed by Syntex Corp (now Roche Bioscience) and is currently being developed by Helsinn and MGI Pharm.
Palonosetron is a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
