1-Methyl-5-p-toluoylpyrrole-2-aceticacid , 10mMinDMSO , 26171-23-3
CAS NO.:26171-23-3
Empirical Formula: C15H15NO3
Molecular Weight: 257.28
MDL number: MFCD00599595
EINECS: 247-497-2
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 156 °C |
Boiling point: | 400.53°C (rough estimate) |
Density | 1.1391 (rough estimate) |
refractive index | 1.5200 (estimate) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | pKa 3.5(H2O
t undefined
I undefined) (Uncertain) |
form | Solid |
color | Off-White to Pale Yellow |
Water Solubility | 222 mg/L |
Description and Uses
An antiinflammatory, analgesic, and antipyretic that is as efficacious as moderate doses of aspirin and better tolerated. Tolmetin produces a number of adverse effects including epigastric pain, dyspepsia, nausea, and vomiting. Tolmetin is approximately 99% plasma protein bound, yet does not interfere with concurrent treatment with oral hypoglycemics. Tolmetin has been found to be effective in the treatment of osteoarthritis and rheumatoid arthritis.
inhibits synthesis of prostaglandins and exhibits expressed analgesic, anti-inflammatory, and fever-reducing properties. It is used for relieving weak to moderate pain in rheumatoid arthritis and osteoarthritis.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H302-H335-H319 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |