A7708712
р-Touidine , AR,99.0% , 106-49-0
Synonym(s):
p-Toluidine;4-Aminotoluene;4-Aminotoluene, 4-Methylaniline;4-Methylaniline
CAS NO.：106-49-0
Empirical Formula: C7H9N
Molecular Weight: 107.15
MDL number: MFCD00007906
EINECS: 203-403-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 41-46 °C(lit.) |
| Boiling point: | 200 °C(lit.) |
| Density | 0.973 g/mL at 25 °C(lit.) |
| vapor density | 3.9 (vs air) |
| vapor pressure | 0.26 mm Hg ( 25 °C) |
| refractive index | 1.5636 |
| Flash point: | 192 °F |
| storage temp. | Store below +30°C. |
| solubility | Soluble in ethanol, pyridine, diethyl ether, acetone, carbon tetrachloride, methanol, carbon disulfide, oils and dilute acids. |
| pka | 5.08(at 25℃) |
| form | powder |
| Specific Gravity | 0.962 |
| color | tan to brown |
| explosive limit | 6.6% |
| Water Solubility | 1.1 g/100 mL |
| Sensitive | Air & Light Sensitive |
| Merck | 14,9536 |
| BRN | 471281 |
| Exposure limits | TLV-TWA skin 2 ppm (～9 mg/m3) (ACGIH);
Suspected Human Carcinogen (ACGIH). |
| Dielectric constant | 4.9800000000000004 |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong acids. |
| LogP | 1.39-1.44 at pH7.4-7.5 |
| CAS DataBase Reference | 106-49-0(CAS DataBase Reference) |
| NIST Chemistry Reference | p-Toluidine(106-49-0) |
| EPA Substance Registry System | p-Toluidine (106-49-0) |
Description and Uses
p-Toluidine is an intermediate in the production of dyes, organic chemicals and aromatic azo compounds. It serves as a component of accelerators for cyanoacrylate glues. Furthermore, it acts as a bidentate Schiff base ligand through condensation with salicylaldehyde. It reacts with catecholamine to form a dye which is useful for spectrophotometric determination of catecholamine drugs.
Safety
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H317-H319-H351-H410 |
| Precautionary statements | P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-36-40-43-50 |
| Safety Statements | 28-36/37-45-61-28A |
| RIDADR | UN 3451 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | XU3150000 |
| F | 8-23 |
| Autoignition Temperature | 899 °F |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 38220000 |
| Hazardous Substances Data | 106-49-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 336 mg/kg LD50 dermal Rabbit 890 mg/kg |
